不同灸量的脐灸疗法对慢阻肺稳定期患者SGRQ评分及肺功能的影响

Effect of umbilical moxibustion with different moxibustion volume on SGRQ score and lung function of chronic obstructive pulmonary disease patients in stable stage

关键词:  脐灸疗法  慢性阻塞性肺疾病  稳定期  圣乔治呼吸问卷  肺功能

Key words:  umbilical moxibustion therapy  chronic obstructive pulmonary disease  stable stage  St. George's respiratory questionnaire  pulmonary function

摘要:

[目的] 分析不同灸量脐灸疗法对慢性阻塞性肺疾病（COPD，简称慢阻肺）稳定期患者圣乔治呼吸问卷（SGRQ）评分及肺功能的影响。[方法] 本研究纳入104例COPD稳定期患者，采取2×2两因素交叉分组设计，按随机数字表法分为4组，每组均治疗2周。比较各组治疗前后SGRQ评分、运动耐力、疗效满意度、肺功能，基于析因设计分析施灸壮数和施灸频次对SGRQ评分的影响。[结果] 1）治疗后，4组SGRQ评分均低于治疗前（P<0.05）；G2组SGRQ评分高于G1组、G4组（P<0.05），G3组SGRQ评分低于G1组、G2组、G4组（P<0.05）。2）治疗后，4组六分钟步行距离（6MWD）均大于治疗前（P<0.05）；G2组6MWD小于G1组、G4组（P<0.05），G3组6MWD大于G1组、G2组、G4组（P<0.05）。3）治疗后，4组COPD患者疗效满意度问卷（ESQ-COPD）评分均高于治疗前（P<0.05）；G3组ESQ-COPD评分高于G1组、G2组、G4组（P<0.05）。4）治疗后，4组第1秒用力呼气量（FEV₁）、FEV₁/用力肺活量（FVC）均大于治疗前（P<0.05）；G2组FEV1、FEV1/FVC均小于G1组、G4组（P<0.05），G3组FEV₁、FEV₁/FVC均大于G1组、G2组、G4组（P<0.05）。5）施灸壮数、施灸频次对治疗前后SGRQ评分变化有影响，且施灸壮数和施灸频次之间存在交互作用，对应最佳组合“3壮、隔日1次”。[结论] 脐灸疗法治疗COPD稳定期患者最佳灸量组合是“3壮、隔日1次”，能改善患者生存质量、肺功能，提高运动耐力、疗效满意度。

Abstract:

[Objective] To analyze the effect of umbilical moxibustion with different moxibustion volume on St. George's respiratory questionnaire(SGRQ) score and pulmonary function of patients with chronic obstructive pulmonary disease (COPD) in stable stage. [Methods] A total of 104 patients with stable COPD were enrolled in this study. They were randomly divided into 4 groups according to the 2×2 two factor crossover design, each group was treated for 2 weeks. SGRQ score, exercise endurance, satisfaction with curative effect and lung function were compared before and after treatment in each group, the effect of number of cones and frequency of moxibustion on SGRQ score was analyzed based on factorial design. [Results] 1)After treatment, SGRQ score of four groups was lower than before treatment (P<0. 05); SGRQ score of group G2 was higher than that of group G1, G4 (P<0. 05), SGRQ score of group G3 was lower than that of group G1, G2, G4 (P<0. 05). 2)After treatment, the 6-minute walk distance (6MWD) in the four groups was greater than that before treatment (P<0. 05); 6MWD in group G2 was less than that in group G1, G4 (P<0. 05), and 6MWD in group G3 was greater than that in group G1, G2, G4 (P<0. 05). 3)After treatment, the score of Effectiveness Satisfaction Questionnaire of COPD (ESQ-COPD) in four groups was higher than that before treatment (P<0. 05); ESQ-COPD score in group G3 was higher than that in group G1, G2, G4 (P<0. 05). 4)After treatment, the forced expiratory volume in one second (FEV1) and FEV1/forced vital capacity (FVC) in four groups were higher than those before treatment (P<0. 05); FEV1 and FEV1/FVC in group G2 were lower than those in group G1, G4 (P<0. 05), FEV1 and FEV1/FVC in group G3 were higher than those in group G1, G2, G4 (P<0. 05). 5)The number of cones and frequency of moxibustion had influence on SGRQ score changes before and after treatment, and there was interaction between the number of cones and frequency of moxibustion, the corresponding best combination was "3 cones, once every other day". [Conclusion] The best moxibustion dose combination of umbilical moxibustion therapy for COPD patients in stable stage is "three cones, once every other day", which can improve the quality of life, lung function, exercise endurance and curative effect satisfaction of patients.